2010

Aktas D, Utine EG, Mrasek K, Weise A, von Eggeling F, Yalaz K, Posorski N, Akarsu N, Alikasifoglu M, Liehr T, Tuncbilek E. Derivative chromosome 1 and GLUT1 deficiency syndrome in a sibling pair Mol Cytogenetics 2010, 3:10.
Al Achkar W, Wafa A, Mkrtchyan H, Moassas F, Liehr T. A rare case of chronic myeloid leukemia with secondary chromosomal changes including partial trisomy 17q21 to 17qter and partial monosomy of 16p13.3. Mol Cytogenet 2010, 3:6.
Al Achkar W, Wafa A, Mkrtchyan H, Moassass F, Liehr T. A rare case of Philadelphia chromosome-positive chronic myelogenous leukemia with inversion in chromosome 9 and t(10;17). Oncol Lett 2010, 1:793-795.
Al Achkar W, Wafa A, Ali BY, Manvelyan M, Liehr T. A rare chronic myeloid leukemia case with Philadelphia chromosome, BCR-ABL e13a3 transcript and complex translocation involving four different chromosomes. Oncol Lett 2010, 1:797-800.
Al Achkar W, Wafa A, Mkrtchyan H, Moassass F, Liehr T. A unique complex translocation involving six different chromosomes in a case of childhood acute lymphoblastic leukemia with the Philadelphia chromosome and adverse prognosis. Oncol Lett 2010, 1:801-804.
Al-Achkar W, Liehr T, Wafa A. Insertion of the 3' ABL region into the long arm of chromosome 1 in a Philadelphia chromosome-negativechronic myeloid leukemia case. Oncol Lett 2010, 1:951-954.
Al Achkar W, Wafa A, Moassass F, Liehr T. Partial trisomy 9p22 to 9p24.2 in combination with partial monosomy 9pter in a Syrian girl. Mol Cytogenet 2010, 3:18.
Al-Achkar W, Wafa A, Manvelyan M, Ikhtiar A, Liehr T. De novo translocation involving two chromosomes in adult prolymphocytic leukemia-A rare case. Leuk Res 2010, 34:e345-347
Alexandrov T, Becker M, Deininger SO, Ernst G, Wehder L, Grasmair M, von EF, Thiele H, Maass P. Spatial Segmentation of Imaging Mass Spectrometry Data with Edge-Preserving Image Denoising and Clustering. J Proteome Res 2010, 9:6535-6546.
Auber B, Burfeind P, Thiels C, Alsat EA, Shoukier M, Liehr T, Nelle H, Bartels I, Salinas-Riester G, Laccone F. An unbalanced translocation resulting in a duplication of Xq28 causes a Rett syndrome-like phenotype in a female patient. Clin Genet 2010, 77:593-597.
Balci S, Yuksel Konuk B, Atik F, Oguz AK, Ergun MA, Baltaci V, Kosyakova N, Liehr T. Partial deletion of the long arm of chromosome 13 (q32q33.2) associated with mental retardation, choanal atresia and fish mouth. Genetic Counselling 2010, 21:317-324.
Barber JC, Bunyan D, Curtis M, Robinson D, Morlot S, Dermitzel A, Liehr T, Alves C, Trindade J, Paramos AI, Cooper C, Ocraft K, Taylor E, Maloney VK. 8p23.1 duplication syndrome differentiated from copy number variation of the defensin cluster at prenatal diagnosis in four new families. Mol Cytogenet 2010, 3:3.
Burégio-Frota P, Valença L, Leal GF, Duarte AR, Bispo-Brito AV, Soares-Ventura EM, Marques-Salles TJ, Nogueira MT, Muniz MT, Silva ML, Hunstig F, Liehr T, Santos N. Identification of a de novo inv dup(X)(pter->q22) by multicolor banding in a girl with Turner syndrome. Genet Mol Res 2010, 9:780-784.
da Silva FE, Cordeiro AB, Nagamachi CY, Pieczarka JC, Rens W, Weise A, Liehr T, Mkrtchyan H, Anselmo NP, de Oliveira EHC. A case of aggressive medulloblastoma with multiple recurrent chromosomal alterations. Cancer Genet Cytogenet 2010, 196:198-200.
de Figueiredo AF, Liehr T, Bhatt S, Binato R, Soares Ventura EM, de Souza MT, Rodrigues Capela de Matos R, Correa Ribeiro R, Abdelhay E, Macedo Silva ML. A new cryptic ins(11;1)(q23;q21q31) detected in a t(1;8;11)(q21;p21;q23) in a baby with acute myeloid leukemia FAB AML-M5. Blood Cells Mol Dis 2010, 45:197-198
de Jesus Marques-Salles T, da Silva Barros JEX, Soares-Ventura EM, Cartaxo-Muniz MT, Santos N, Ferreira E, Macedo Silva ML, Liehr T, Mkrtchyan H. Unusual childhood biphenotypic acute leukemia with a yet unreported t(3;13)(p25.1;q13). Leuk Res 2010, 34: e206-e207.
de Jesus Marques-Salles T, Mkrtchyan H, Pereira Leite E, Soares-Ventura EM, Cartaxo-Muniz MT, Ferreira E, Liehr T, Macedo Silva ML, Santos N. Complex karyotype defined by FISH and M-FISH studies in an infant with acute megakarioblastic leukemia and neurofibromatosis. Cancer Genet Cytogenet 2010, 200: 167-169.
Dittmar Y, Posorski N, Rauchfuss F, Voigt R, Heise M, Jandt K, Gajda M, Settmacher U. Relationship between degree of chromosomal aberration and survival in intestinal-type gastric cancer - a preliminary report based on three cases of hepatic metastasized gastric cancer with long-time survival. Onkologie 2010, 33:591-596.
Egritas O, Cavdarli B, Dalgic B, Ergun MA, Percin F, Ziegler M, Pohle B, Liehr T. Duplication 4q associated with chronic cholestatic changes in liver biopsy. Eur J Med Genet 2010, 53:411-414.
Escher N, Ernst G, Melle C, Berndt A, Clement JH, Junker K, Friedrich K, Guntinas-Lichius O, von Eggeling F. Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS). Diagn Pathol 2010, 5:10.
Ewers E, Yoda K, Hamid AB, Weise A, Manvelyan M, Liehr T. Centromere activity in dicentric small supernumerary marker chromosomes. Chromosome Research 2010; 18:555-562.
Fernández-Toral J, Rodríguez L, Plasencia A, Martínez-Frías ML, Ewers E, Hamid AB, Ziegler M, Liehr T. Four small supernumerary marker chromosomes derived from chromosomes 6, 8, 11 and 12 in a patient with minimal clinical abnormalities - a case report. J Med Case Reports 2010, 4:239.
Ferreira SI, Matoso E, Pinto M, Almeida J, Liehr T, Melo JB, Carreira IM. X-chromosome terminal deletion in a female with premature ovarian failure: Haploinsufficiency of X-linked genes as a possible explanation. Mol Cytogenet 2010, 3:14.
Fousteris MA, Schubert U, Roell D, Roediger J, Bailis N, Nikolaropoulos SS, Baniahmad A, Giannis A. 20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth. Bioorg Med Chem 2010, 18:6960-6969.
Gersak K, Writzl K, Veble A, Liehr T. Primary amenorrhoea in a patient with mosaicism for monosomy X and a derivative X-chromosome. Genet Couns 2010, 21:335-342.
Gorsler T, Murzik U, Ulbricht T, Hentschel J, Hemmerich P, Melle C. DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferation. BMC Cell Biol 2010, 11:100.
Jung MJ, Murzik U, Wehder L, Hemmerich P, Melle C. Regulation of cellular actin architecture by S100A10. Exp Cell Res 2010, 316:1234-1240.
Karaer K, Ergun MA, Weise A, Ewers E, Liehr T, Kosyakova N, Mkrtchyan H. The case of an infertile male with an uncommon reciprocal X-autosomal translocation: how does this affect male fertility? Genet Couns 2010, 21:397-404
Kim HG, Ahn JW, Kurth I, Ullmann R, Kim HT, Kulharya A, Ha KS, Itokawa Y, Meliciani I, Wenzel W, Lee D, Rosenberger G, Ozata M, Bick DP, Sherins RJ, Nagase T, Tekin M, Kim SH, Kim CH, Ropers HH, Gusella JF, Kalscheuer V, Choi CY, Layman LC. WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. Am J Hum Genet 2010, 87:465-479.
Ktistaki E, Garefalaki A, Williams A, Andrews SR, Bell DM, Foster KE, Spilianakis CG, Flavell RA, Kosyakova N, Trifonov V, Liehr T, Kioussis D. CD8 locus nuclear dynamics during thymocyte development. J Immunol 2010, 184:5686-5695.
Kyrylenko S, Baniahmad A. Sirtuin family: a link to metabolic signaling and senescence. Curr Med Chem 2010, 17:2921-2932.
Li Z, Zhang Q, Mao J-H, Weise A, Mrasek K, Fan X, Zhang X, Liehr T, Lu KH, Balmain A, Cai W-W. A HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis. Oncogene 2010, 29:2659-2671.
Liehr T. Cytogenetic contribution to uniparental disomy (UPD). Mol Cytogenet 2010, 3:8.
Liehr T. A new internet page on uniparental disomy. ECA-newsletter 2010, 26:22-24
Liehr T, Kosyakova N, Weise A, Ziegler M, Raabe-Meyer G. First case of a neocentromere formation in an otherwise normal chromosome 7. Cytogenet Genome Res 2010, 218: 189-191.
Liehr T, Wegner R-D, Stumm M, Martin T, Gillessen-Kaesbach G, Kosyakova N, Ewers E, Hamid AB, von Eggeling F, Hentschel J, Ziegler M, Weise A. Three new cases with small supernumerary marker chromosomes 1 and normal phenotype. J Chin Med Assoc 2010, 73: 205-207.
Liehr T, Karamysheva T, Merkas M, Brecevic L, Hamid AB, Ewers E, Mrasek K, Kosyakova N, Weise A. Somatic mosaicism in cases with small supernumerary marker chromosomes. Curr Genomics 2010, 11:432-439
Manolakis E, Peitsidis P, Elefteriades M, Dedoulis E, Ziegler M, Orru S, Liehr T, Petersen MB. Prenatal detection of full monosomy 21 in a fetus with an increased nuchal translucency. Molecular cytogenetic analysis and review of the literature. J Obstet Gynaecol Res 2010, 36: 435-440.
Manolakos E, Kefalas K, Neroutsou R, Lagou M, Kosyakova N, Ewers E, Ziegler M, Weise A, Tsoplou P, Rapti S-M, Papoulidis I, Anastasakis E, Garas A, Sotiriou S, Eleftheriades M, Peitsidis P, Μalathrakis D, Thomaidis L, Kitsos G, Orru S,Liehr T, Petersen MB, Kitsiou-Tzeli S. Characterization of 23 small supernumerary marker chromosomes detected at pre-natal diagnosis: The value of fluorescence in situ hybridization Mol Med Rep 2010, 3:1015-1022.
Manolakos E, Vetro A, Kefalas K, Rapti SM, Louizou E, Garas A, Kitsos G, Vasileiadis L, Tsoplou P, Eleftheriades M, Peitsidis P, Orru S, Liehr T, Petersen MB, Thomaidis L. The use of array-CGH in a cohort of Greek children with developmental delay. Mol Cytogenet 2010, 3:22.
Mkrtchyan H, Garcia Ney DR, de Ventura ES, Liehr T, Felix GR, de Jesus Marques-Salles T, Abdelhay E, Macedo Silva ML. Molecular cytogenetic studies characterize near-triploid complex karyotype in a child with acute lymphoblastic leukemia. Cancer Genet 2010, 197:71-74.
Mkrtchyan H, Gross M, Hinreiner S, Polytiko A, Manvelyan M, Mrasek K, Kosyakova N, Ewers E, Nelle H, Liehr T, Volleth M, Weise A. Early embryonic chromosome instability results in stable mosaic pattern in human tissues. PLoS ONE 2010, 5: e9591.
Mkrtchyan H, Gross M, Hinreiner S, Polytiko A, Manvelyan M, Mrasek K, Kosyakova N, Ewers E, Nelle H, Liehr T, Bhatt S, Thoma K, Gebhart E, Wilhelm S, Fahsold R, Volleth M, Weise A. The human genome puzzle - the role of copy number variation in somatic mosaicism. Curr Genomics 2010, 11:426-431.
Mrasek K, Schoder C, Teichmann AC, Behr K, Franze B, Wilhelm K, Blaurock N, Claussen U, Liehr T, Weise A. Global screening and extended nomenclature for 230 aphidicolin-inducible fragile sites, including 61 yet unreported ones. Int J Oncol 2010,36:929-40.
Nelle H, Schreyer I, Ewers E, Mrasek K, Kosyakova N, Merkas M, Hamid AB, Weise A, Liehr T. Harmless familial small supernumerary marker chromosome 22 hampers diagnosis of fragile X-syndrome. Molecular Medicine Reports 2010, 3:571-574.
Niksic SB, Deretic VI, Pilic GR, Ewers E, Merkas M, Ziegler M, Liehr T. Trisomy 21 with a small supernumerary marker chromosome derived from chromosomes 13/21 and 18. Balk J Med Genet 2010, 13:55-58.
Papaioannou M, Schleich S, Roell D, Schubert U, Tanner T, Claessens F, Matusch R, Baniahmad A. NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. Invest New Drugs, 28:729-743.
Papoulidis I, Manolakos E, Siomou E, Kefalas K, Thomaidis L, Liehr T, Vetro A, Athanasiadis A, Zuffardi O, Petersen MB. A fetus with ring chromosome 21 characterized by aCGH shows no clinical findings after birth. Prenat Diag 2010, 30:586-588.
Polityko A, Khurs O, Rumyantseva N, Naumchik I, Kosyakova N, Tönnies H, Sperling K, Neitzel H, Weise A, Liehr T. Two siblings with immunodeficiency, facial abnormalities and chromosomal instability without mutation in DNMT3B gene but liability towards malignancy; a new chromatin disorder delineation? Mol Cytogenet 2010, 3:5
Santos M, Mrasek K, Madrigal I, Martorell MR, González-Meneses A, Rodríguez-Criado G, Milŕ M, Liehr T, Fuster C. Characterisation of a complex cryptic mosaicism for an sSMC derived from the X chromosome present in a boy with congenital malformations. Am J Med Genet 2010, 152A:2161-2163.
Schaffrath Rosario A, Kurth BM, Stolzenberg H, Ellert U, Neuhauser H. Body mass index percentiles for children and adolescents in Germany based on a nationally representative sample (KiGGS 2003-2006). Eur J Clin Nutr 2010, 64:341-349.
Schoder C, Liehr T, Velleuer E, Wilhelm K, Blaurock N, Weise A, Mrasek K. New aspects on chromosomal instability: chromosomal break-points in Fanconi anemia patients co-localize on the molecular level with fragile sites. Int J Oncol 2010, 36:307-312
Soehn AS, Franck T, Biskup S, Giaime E, Melle C, Rott R, Cebo D, Kalbacher H, Ott E, Pahnke J, Meitinger T, Krüger R, Gasser T, Berg D, von Eggeling F, Engelender S, da Costa CA, Riess O. Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease. Neurogenetics 2010, 11:203-215.
Trifonov VA, Kosyakova N, Romanenko SA, Graphodatsky AS, Liehr T. New insights into the karyotypic evolution in muroid rodents revealed by multicolor banding applying murine probes. Chr Res 2010, 18:265-275.
Uz E, Alanay Y, Aktas D, Vargel I, Gucer S, Tuncbilek G, von Eggeling F, Yilmaz E, Deren O, Posorski N, Ozdag H, Liehr T, Balci S, Alikasifoglu M, Wollnik B, Akarsu NK. Disruption of paired-tail homeobox gene ALX1 (Cart1) causes Extreme microphthalmia and severe facial clefting: expanding the spectrum of autosomal recessive ALX-related frontonasal dysplasia. Am J Hum Genet 2010, 86:789-796.
Walter M, Heinze C, Steiner T, Pilchowski R, von Eggeling F, Wunderlich H, Junker K. Immunochemotherapy-associated protein patterns in tumour tissue and serum of patients with metastatic renal cell carcinoma. Arch Physiol Biochem 2010, 116:197-207.
Wehder L, Ernst G, Crecelius AC, Guntinas-Lichius O, Melle C, Schubert US, von Eggeling F. Depicting the spatial distribution of proteins in human tumor tissue combining SELDI and MALDI imaging and immunohistochemistry. J Histochem Cytochem 2010, 58:929-937.
Weise A, Timmermann B, Grabherr M, Werber M, Heyn P, Kosyakova N, Liehr T, Neitzel H, Konrat K, Bommer C, Dietrich C, Rajab A, Reinhardt R, Mundlos S, Lindner TH, Hoffmann K. High-throughput sequencing of microdissected chromosomal regions. Eur J Hum Genet 2010, 18:457-462.