Die Forschungsprojekte von NeurInfect sind translational und interdisziplinär aufgebaut. In eng verzahnten experimentellen und klinischen Teilprojekten untersuchen wir, wie respiratorische Infektionen neuronale Netzwerke, Immunantworten und die Gehirn-Körper-Kommunikation beeinflussen. Harmonisiert genutzte Patientenkohorten, etablierte Tiermodelle und eine gemeinsam genutzte methodische Infrastruktur ermöglichen projektübergreifende Vergleiche und eine exzellente Ausbildung der Promovierenden.
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P1: Nils Opel, Mathias Pletz: |
Unraveling the dynamic relationship between systemic inflammation and brain network dysfunction during acute pneumonia and recovery |
| P3: Kathrin Finke, Martin Walter: | Early detection of neurocognitive changes in patients with pneumonia |
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P5: Nils Opel: |
Metabolic dysregulation as a moderator of neuropsychiatric sequelae following respiratory infection |
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P6: Veronika Engert: |
The role of stress and social abilities in the trajectory from respiratory infection to neuropsychiatric impairment |
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P8: Manja Marz, Andreas Stallmach: |
Trajectories of host virome/microbiome interaction with neuropsychiatric sequelae following respiratory infection |
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P2: Christian Geis, Martin Witzenrath: |
Impact of pneumonia and mechanical ventilation on immune-neuronal interaction and hippocampal circuit dysfunction | |
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P4: Christina Ehrhardt, Christoph Schmidt-Hieber: |
Inflammation modulates hippocampal memory processing following viral respiratory infection | |
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P7: Geraldine Nouailles, Sebastian Weis: |
Exploring the role of stress, metabolism, and age on long-term cognitive impairment following pneumococcal pneumonia | |
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P9: Ilse Jacobsen, Christian Geis: |
Effects of the gut microbiome modification on infection and inflammation-induced cognitive dysfunction |
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P10: Manja Marz: |
Role of small extracellular vesicles in humoral body-brain communication in respiratory infection |
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P11: |
Relevance of the memory T cell repertoire for the development of neuropsychiatric sequelae after respiratory infection |