Zur Startseite Zur Hauptnavigation Zum Inhalt Zur Sitemap
+A-
ENDE
  menu
Institut für Allgemeinmedizin
  menu
  • Homepage
  • Team
  • Research areas
    • Quantitative Health Services Research
      • Team
      • Research Projects
  • Research projects
  • Publications
  • Main menu
    • Patients & Relatives
    • Research
    • Teaching and study
    • Doctors & Referrers
    • Clinics & Institutes
    • Careers
    • University Hospital
  • Homepage
  • Team
  • Research areas
    • Quantitative Health Services Research
      • Team
      • Research Projects
  • Research projects
  • Publications
Homepage / Research areas / Quantitative Health Services Research / Research Projects

Research Projects

Research Projects

UFO

UFO - Recording of undesirable treatment outcomes after surgery from the patient's perspective

Funding period: 01/2025-06/2028 (42 months)
Funding code: 01VSF24018
Funding body: Gemeinsamer Bundesausschuss Innovationsausschuss

 

Study Objective

The aim of UFO is the early detection and long-term reduction of postoperative complications. To this end, the project team is developing a survey instrument that systematically captures non-desirable treatment outcomes after surgery (UFOs) using patient-reported outcome measures (PROMs). This will enable:

  • a comparison and benchmarking of postoperative outcomes between outpatient and inpatient surgeries.
  • the early detection of postoperative complications, enabling targeted follow-up care and early intervention.

 

Subgroups of the Institute of General Medicine

Routine Data Analysis
To support the project, we analyze BARMER claims data with the following objectives:

  • Identifying frequently performed outpatient surgical procedures to facilitate an evidence-based selection of relevant procedures for PROM (Patient-Reported Outcome Measures) assessment.
  • Mapping postoperative complications of the selected procedures via routine administrative data using:
    • ICD-10 codes for complications (e.g., hemorrhages, postoperative infections)
    • ATC codes for analgesic prescriptions (e.g., opioids, anti-inflammatory drugs)
    • Hospital readmissions within 30 to 90 days
    • Secondary surgical interventions indicative of a complication
  • Identifying patient-specific risk factors associated with an increased likelihood of complications.
  • Analyzing regional variations in UFO rates to detect potential differences in healthcare quality and geographic patterns.

Patient Involvement
The perspectives and firsthand experiences of patients undergoing surgical procedures play a central role in the project. Therefore, the initiative is continuously supported by a Patient Advisory Board. During advisory board meetings, researchers and patients collaboratively deliberate on project content, methodological approaches, and findings. For instance, patients provide insight into experienced symptoms of impending complications or share their experiences regarding inpatient and outpatient postoperative care. These insights directly inform the development of the survey instrument.
Patient involvement within the UFO project is integrated into the initiative "Joint Research with Citizens" of the Institute of General Practice and the "Patient Involvement" Working Group of the Center for Health Services Research. Furthermore, in collaboration with general practitioners through the RESPoNsE Teaching and Research Practice Network of the Institute of General Practice, we are exploring how the developed survey instrument can be integrated into postoperative follow-up care.
Would you like to participate in the project as a patient or general practitioner, or do you have feedback for us? Please let us know. Contact:

Projekt team

 

  • Prof. Dr. Verena Vogt
  • Meik Hildebrand, M.Sc.
  • Anni Matthes, M.Sc.
  • Richard Schmidt
  • Josephine Storch, M.Sc.
  • Prof. Dr. med. J. Bleidorn

Consortium Partner

  • Klinik für Anästhesiologie und Intensivmedizin (KAI), Universitätsklinikum Jena: apl. Prof. Dr. Winfried Meißner (Projektleitung, Konsortialführung)
  • Bundesverband für Ambulantes Operieren e.V. (BAO)
  • BARMER
  • Deutsche Gesellschaft für Anäesthesiologie und Intensivmedizin (DGAI)
  • Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV)

Cooperation partner

  • Aktionsbündnis für Patientensicherheit (APS)

DIAMANT

DIAMANT-SD:

Thyroid diagnostics in outpatient care

 

Funding period: 04/2025-03/2028
Funding code: 01VSF24050
Funding body: Innovationsfonds  

Study Objective

The DEGAM guideline „Erhöhter TSH-Wert in der Hausarztpraxis“ includes recommendations that explicitly call for the avoidance of overdiagnosis: in the case of elevated TSH levels, no measurement of fT3 should be performed, and ultrasound examination of the thyroid gland is also not indicated. However, this knowledge has not yet been sufficiently translated into practice: around one third of laboratory tests for monitoring thyroid disease are not performed in accordance with the guidelines, and ultrasound examinations carried out too early lead to unnecessary follow-up examinations and treatments.

The aim of the DIAMANT-SD project is to develop and assess the feasibility of an intervention providing decision-making aids for thyroid-specific laboratory tests and ultrasounds. The so-called “Diagnostic Box” is intended to equip doctors and patients with tools to assess the necessity and risks of diagnostic tests with greater certainty. The Diagnostic Box aims to help reduce the use of unnecessary diagnostics. The project proceeds as follows:

Development of a Diagnostic Box: With the involvement of general practitioners, specialist physicians, patients, and citizens, a Diagnostic Box will be developed. The Diagnostic Box contains: (1) training on thyroid diagnostics, overdiagnosis and risk communication, (2) informational materials for patients on thyroid-related laboratory tests and ultrasound, (3) the arriba

  1. tool for risk assessment and communication regarding thyroid ultrasound, and (4) peer comparison feedback on laboratory tests and ultrasound.
  2. Feasibility Study: The impact of the Diagnostic Box on healthcare delivery will be estimated in a cluster-randomised study to measure the success of the intervention. Practices that play a significant role in primary care will be included. The feasibility evaluation (recruitment, randomisation, intervention, follow-up assessments) serves to prepare for a possible subsequent intervention study.
  3. Long-term Implementation Strategies: Strategies for the sustainable integration of the intervention into medical practice will be developed.

The project will be funded with €1.5 million over three years and has started in April 2025.

Subprojects of the Institute of General Practice

Feasibility study

  • Piloting a randomized study at the level of medical practices

Evaluation

  • Exploratory analysis of efficacy based on the pilot study
    • Can the intervention lead to a reduction in the utilization of diagnostic tests?
    • How can this be measured reliably?
  • Piloting the health economic evaluation

Development of implementation strategies

  • Presentation of the healthcare situation of patients with thyroid diseases using statutory health insurance (SHI) routine data
    • Presentation of care pathways using sequence analysis
    • Analysis of patient groups with similar care needs and patterns using sequence analysis
  • Modeling and analysis of the transferability of the diagnostic box into standard care

Project Team

  • Prof. Dr. Verena Vogt
  • Meik Hildebrandt, M.Sc.
  • Kristina Söhl, MPH

Cooperation Partners

  • Institute of General Practice, University Hospital Erlangen: Dr. phil. Susann Hueber, Dr. med. Lisette Warkentin, and Prof. Dr. Thomas Kuehlein (Consortium Lead)
  • Faculty of Medicine Carl Gustav Carus, Department of General Practice, Technische Universitaet Dresden: Dr. Dipl.-Soz. Karen Voigt
  •  MPH, Dr. Jeannine Schuebel
  • GWQ ServicePlus AG, Duesseldorf
  • Association of Statutory Health Insurance Physicians of Thuringia (KVT), Weimar

Literatur

[1] Schübel J, Voigt K, Uebel T. Erhöhter TSH-Wert in der Hausarztpraxis: S2k-Leitlinie: Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin e.V; 2023. https://www.degam.de/leitlinie-s2k-053-046.

[2] Hueber S, Biermann V, Tomandl J, Warkentin L, Schedlbauer A, Tauchmann H, Klemperer D, Lehmann M, Donnachie E, Kühlein T. Consequences of early thyroid ultrasound on subsequent tests, morbidity and costs: an explorative analysis of routine health data from German ambulatory care. BMJ Open. 2023;13(3):e059016. DOI:10.1136/bmjopen-2021-059016

[3] Hildebrandt M, Pioch C, Dammertz L, Ihle P, Nothacker M, Schneider U, Swart E, Busse R, Vogt V. Quantifying Low-Value Care in Germany: An Observational Study Using Statutory Health Insurance Data From 2018 to 2021. Value in Health. 2024. https://doi.org/10.1016/j.jval.2024.10.3852 .

REMIT

still under development

DIVA

DIVA - Digital networking in conservative ophthalmology

Funding period: 07/2025 - 12/2028 (42 months)
Funding code: 01NVF24316
Funding body: Gemeinsamer Bundesausschuss Innovationsausschuss
 

Study Objective

In Thuringia, a federal state of Germany, up to 54 percent of people with type 1 or type 2 diabetes mellitus who are covered by statutory health insurance do not receive the recommended ophthalmological screening (diabetic retinopathy screening) for the early detection of diabetic retinal disease. In economically depraved regions in particular, there is a shortfall in care, which exposes those affected to an increased risk of undetected and progressive retinal damage.

The primary aim of the DIVA project is to increase the screening rate for diabetic retinopathy in underserved regions of Thuringia by means of a new form of healthcare delivery (‘Neue Versorgungsform’, NVF). Through telemedical examination of the ocular fundus, pathological retinal changes can be detected at an early stage in order to prevent severe disease progression and make more efficient use of ophthalmological resources.

The project will be funded with €6.2 million over three and a half years and has started in summer 2025. If successfully implemented, telemedicine-supported retinal examinations could be incorporated into routine care in the long term and established as a model for further telemedicine applications.

Subprojects of the Institute of General Practice

The introduction of the new form of care (NVF) is being evaluated within the framework of an accompanying scientific study by the Quantitative Health Services Research working group of the Institute of General Practice. The evaluation covers the following key areas:

  • Screening rates: Does the introduction of the NVF lead to a higher rate of fundus screening examinations among statutorily insured individuals with diabetes mellitus in underserved regions of Thuringia?
  • Impact on ophthalmological capacities: Does the NVF relieve ophthalmic practices and create capacity for other necessary treatments?
  • Implementation in practice: How effectively can the NVF be integrated into existing healthcare structures?
  • Participant satisfaction: How do patients and healthcare professionals rate the new form of care?
  • Cost-effectiveness: Is the NVF economically viable compared to conventional ophthalmic care?

Project Team

  • Prof. Dr. Verena Vogt
  • Richard Schmidt
  • Dr. rer. nat. Robby Markwart
  • Dr. rer. medic. Sarah Salomo

Consortium Lead

Association of Statutory Health Insurance Physicians of Thuringia (KV Thuringia)

Cooperation Partners

  • Universitätsklinikum Jena, Institut für Allgemeinmedizin
  • BARMER
  • DAK-Gesundheit
  • Techniker Krankenkasse

Cooperating Health Insurance Companies

  • AOK PLUS
  • KKH
  • BKK Landesverband Mitte
Homepage Publications
Team
Research areas
Research projects