Publikationen
2026
Born S, Rose N, Piedmont S, Schwarzkopf D, Pletz MW, Abels W, Reinhart K, Fleischmann-Struzek C. The Role of Perceived Urgency and Barriers in Using Emergency Medical Care for Sepsis: A German-Wide, Representative Survey Using Case Vignettes. Crit Care Med. 2026 Feb 1;54(2):291-300. doi: 10.1097/CCM.0000000000006967. Epub 2025 Dec 3. PMID: 41342620; PMCID: PMC12955971.
GBD 2021 Global Sepsis Collaborators. Global, regional, and national sepsis incidence and mortality, 1990-2021: a systematic analysis. Lancet Glob Health. 2025 Dec;13(12):e2013-e2026. doi: 10.1016/S2214-109X(25)00356-0. Epub 2025 Oct 21. Erratum in: Lancet Glob Health. 2026 Feb;14(2):e198. doi: 10.1016/S2214-109X(25)00486-3. PMID: 41135560.
Joost FEA, Rose N, Kimmig A, Ruhnke T, Dröge P, Freytag A, Günster C, Pletz MW, Roesler M, Reuken PA, Schlattmann P, Schmidt KFR, Stallmach A, Storch J, Reinhart K, Wedekind L, Fleischmann-Struzek C. Long-term outcomes after intensive care unit-treated COVID-19, influenza and respiratory sepsis in 2020 - a comparative, population-based cohort study. Infection. 2026 Feb;54(1):179-189. doi: 10.1007/s15010-025-02644-3. Epub 2025 Oct 3. PMID: 41042487; PMCID: PMC12864265.
Thomas-Rüddel D, Rose N, Fleischmann-Struzek C, Reinhart K, Boden B, Dorow H, Edel A, Gonnert FA, Götz J, Gründling M, Heim M, Holbeck K, Jaschinski U, Koch C, Künzer C, Le Ngoc K, Lindau S, Mehlmann NB, Meybohm P, Neb H, Nordine M, Ouart D, Putensen C, Sander M, Schewe JC, Schlattmann P, Schmidt G, Schneider G, Spies C, Steinsberger F, Tam C, Zacharowski K, Zinn S, Schwarzkopf D. Think sepsis, write sepsis, code sepsis – patient characteristics associated with sepsis (under-)coding in administrative health data. Infection. 2026 Feb;54(1):421-432. doi: 10.1007/s15010-025-02685-8. Epub 2025 Dec 8. PMID: 41359203; PMCID: PMC12864231.
Vardon F, Fleischmann-Struzek C, Latronico N, Cinotti R. Post-intensive care syndrome. What clinicians and researchers must know. Anaesth Crit Care Pain Med. 2026 Jan;45(1):101620. doi: 10.1016/j.accpm.2025.101620. Epub 2025 Sep 27. PMID: 41022213.
2025
Bircak-Kuchtova B, Rose N, Geis C, Finke K, Pletz MW, Chung HY, Fleischmann-Struzek C. Effectiveness of targeted post-acute interventions and follow-up services for sepsis survivors: a systematic review. Crit Care. 2025 Aug 8;29(1):351. doi: 10.1186/s13054-025-05585-3. PMID: 40781720; PMCID: PMC12333265.
Draeger L, Fleischmann-Struzek C, Bleidorn J, Kannengiesser L, Schmidt K, Apfelbacher C, Matthaeus-Kraemer C. Healthcare Professionals' Perspectives on Sepsis Care Pathways-Qualitative Pilot Expert Interviews. J Clin Med. 2025 Jan 18;14(2):619. doi: 10.3390/jcm14020619. PMID: 39860625; PMCID: PMC11766067.
Draeger L, Fleischmann-Struzek C, Gehrke-Beck S, Heintze C, Thomas-Rueddel DO, Schmidt K. Barriers and facilitators to optimal sepsis care - a systematized review of healthcare professionals' perspectives. BMC Health Serv Res. 2025 Apr 24;25(1):591. doi: 10.1186/s12913-025-12777-8. PMID: 40275226; PMCID: PMC12020105.
Dreiling J, Komann M, Rose N, Meißner W, Kubulus C, Volk T, Schwarzkopf D. Quality assurance in perioperative acute pain therapy: The validity of claims data compared to registry data. Deutsches Ärzteblatt International. 2025 122: 334–5. DOI: 10.3238/arztebl.m2025.0061
Gheitasi R, Baumgart S, Roell D, Rose N, Watzl C, Dudziak D, Andreas N, Makarewicz O, Drube S, Schnizer C, Kamradt T, Weis S, Pletz MW. Age- and sex-associated differences in immune cell populations. iScience. 2025 28(8),113092. doi: 10.1016/j.isci.2025.113092.
Herrmann E, Schindehütte M, Kindl G, Reinhold AK, Aulbach F, Rose N, Dreiling J, Schwarzkopf D, Meir M, Jin Y, Teichmüller K, Widder A, Blum R, Sawalma A, Cebulla N, Sendtner M, Meissner W, Brack A, Pham M, Sommer C, Schlegel N, Rittner HL. Chronic postsurgical inguinal pain: incidence and diagnostic biomarkers from a large German national claims database. Br J Anaesth. 2025 Jun;134(6):1746-1755. doi: 10.1016/j.bja.2024.11.048. PMID: 39909798; PMCID: PMC12106889.
Komann M, Arnold C, Dreiling JT, Rose N, Kubulus C, Volk T, Baumbach P, Fleischmann-Struzek C, Meißner W, Schwarzkopf D. How perioperative processes and patient-reported outcomes contribute to persistent postoperative opioid use: A cohort study linking clinical and health claims data. Eur J Anaesthesiol. 2025 Nov 1;42(11):997-1005. doi: 10.1097/EJA.0000000000002265. Epub 2025 Sep 3. PMID: 40905237.
Kubulus C, Komann M, Paxian M, Schubert AK, Schwarzkopf D, Rose N, Meissner W, Marschall U, Dreiling J, Fleischmann-Struzek C, Volk T; net-ra investigators. Does the quality of pain relief after major surgery influence the risk of postoperative complications? A prospective observational study. PLoS One. 2025 Sep 23;20(9):e0332866. doi: 10.1371/journal.pone.0332866. PMID: 40986535; PMCID: PMC12456833.
Rose N, Agrama I, Nachtigall I, Pletz MW, Rosendahl J, Chung HY, Zielinski CE, Dudziak D, Spoden M, Dröge P, Hagel S, Fleischmann-Struzek C. Sex differences in sepsis outcomes across the lifespan: a population-based cohort study in Germany. Crit Care. 2025 Sep 26;29(1):408. doi: 10.1186/s13054-025-05657-4. PMID: 41013702; PMCID: PMC12476041.
Ruhnke T, Storch J, Freytag A, Rose N, Kimmig A, Dröge P, Wedekind L, Günster C, Goldhahn L, Swart E, Pletz MW, Reinhart K, Schlattmann P, Fleischmann-Struzek C. Transitional care after hospitalization for sepsis in Germany- results from the population-based AVENIR cohort study. Infection. 2025 Dec;53(6):2533-2542. doi: 10.1007/s15010-025-02589-7. Epub 2025 Jul 8. PMID: 40627302; PMCID: PMC12675533.
Sell S, Fleischmann-Struzek C, Spoden M, Rosendahl J. Mental health in the first year after ICU-treated sepsis: Analysis of administrative diagnoses in German health claims data. Gen Hosp Psychiatry. 2025 Mar-Apr;93:109-115. doi: 10.1016/j.genhosppsych.2025.02.001. Epub 2025 Feb 7. PMID: 39923305.
Spott R, Pletz MW, Fleischmann-Struzek C, Kimmig A, Hadlich C, Hauert M, Lohde M, Jundzill M, Marquet M, Dickmann P, Schüchner R, Hölzer M, Kühnert D, Brandt C. Leveraging mobility data to analyze persistent SARS-CoV-2 mutations and inform targeted genomic surveillance. Elife. 2025 Jan 15;13:RP94045. doi: 10.7554/eLife.94045. PMID: 39812649; PMCID: PMC11735024.
Vahl F, Ullmann S, Draeger L, Kannengießer L, Pletz MW, Matthaeus-Kraemer C, Fleischmann-Struzek C. "Lost in Transition": Informational Needs of Sepsis Survivors and Their Relatives Across the Care Trajectory-A Qualitative Study. J Clin Med. 2025 Dec 23;15(1):91. doi: 10.3390/jcm15010091. PMID: 41517340; PMCID: PMC12787246.
Wedekind L, Rose N, Freytag A, Kimmig A, Schlattmann P, Pletz MW, Ruhnke T, Dröge P, Fleischmann-Struzek C. Rehospitalizations for ambulatory care sensitive conditions in sepsis survivors- a nationwide cohort study using health claims data 2016-2019. Infection. 2025 Oct;53(5):2227-2233. doi: 10.1007/s15010-025-02606-9. Epub 2025 Jul 18. PMID: 40679743; PMCID: PMC12460434.
2024
Abels W, Reinhart K, Neugebauer E, Wulkotte E, Toubekis E, Piedmont S, Born S, Rieck T, Wegwarth O, Spies C, Schlattmann P, Schwarzkopf D, Fleischmann-Struzek C. Improving prevention and early detection of sepsis among patient groups at risk: Introducing a model for a multimodal information campaign-The SepWiss study protocol. PLoS One. 2024 Jul 17;19(7):e0305107. doi: 10.1371/journal.pone.0305107. PMID: 39018297; PMCID: PMC11253930.
Bahrs C, Schönherr C, Panning M, Rose N, Dähne T, Hagel S, Weis S, Rupp J, Rohde G, Witzenrath M, Pletz MW; CAPNETZ Study Group. Frequency and clinical significance of Herpes simplex virus type 1/2 reactivation in adult patients with mild to moderately severe community-acquired pneumonia: a multicentre cohort study. Infection. 2024 Jul 20. doi: 10.1007/s15010-024-02351-5. Epub ahead of print. PMID: 39033207.
Born S, Schwarzkopf D, Rose N, Pletz MW, Reinhart K, Fleischmann-Struzek C. Changes in Attitudes towards Influenza and Pneumococcal Vaccination during the Subsiding COVID-19 Pandemic-Results of a Longitudinal Survey Study among Risk Groups in Germany between 2021 and 2023. Vaccines (Basel). 2024 Sep 21;12(9):1080. doi: 10.3390/vaccines12091080. PMID: 39340110; PMCID: PMC11435497.
Dreiling J, Rose N, Arnold C, Baumbach P, Fleischmann-Struzek C, Kubulus C, Komann M, Marschall U, Rittner HL, Volk T, Meissner W, Schwarzkopf D. The Incidence and Risk Factors of Persistent Opioid Use After Surgery—a Retrospective Secondary Data Analysis. Dtsch Arztebl Int. 2024 Nov 15;(Forthcoming):arztebl.m2024.0200. doi: 10.3238/arztebl.m2024.0200. Epub ahead of print. PMID: 39356103.
Fleischmann-Struzek C, Joost FEA, Pletz MW, Weiß B, Paul N, Ely EW, Reinhart K, Rose N. How are Long-Covid, Post-Sepsis-Syndrome and Post-Intensive-Care-Syndrome related? A conceptional approach based on the current research literature. Crit Care. 2024 Aug 29;28(1):283. doi: 10.1186/s13054-024-05076-x. PMID: 39210399; PMCID: PMC11363639.
Fleischmann-Struzek C, Rose N, Ditscheid B, Draeger L, Dröge P, Freytag A, Goldhahn L, Kannengießer L, Kimmig A, Matthäus-Krämer C, Ruhnke T, Reinhart K, Schlattmann P, Schmidt K, Storch J, Ulbrich R, Ullmann S, Wedekind L, Swart E. Understanding health care pathways of patients with sepsis: protocol of a mixed-methods analysis of health care utilization, experiences, and needs of patients with and after sepsis. BMC Health Services Research 2024, 24(1), 40.
Fleischmann-Struzek C, Born S, Kesselmeier M, Ely EW, Töpfer K, Romeike H, Bauer M, Bercker S, Bodechtel U, Fiedler S, Groesdonk HV, Petros S, Platzer S, Rüddel H, Schreiber T, Reinhart K, Scherag A. Functional dependence following intensive care unit-treated sepsis: three-year follow-up results from the prospective Mid-German Sepsis Cohort (MSC). Lancet Reg Health Eur. 2024 Sep 12;46:101066. doi: 10.1016/j.lanepe.2024.101066. PMID: 39308983; PMCID: PMC11415812.
Herrmann E, Schindehütte M, Kindl G, Reinhold AK, Aulbach F, Rose N, Dreiling J, Schwarzkopf D, Meir M, Jin Y, Teichmüller K, Widder A, Blum R, Sawalma A, Cebulla N, Sendtner M, Meissner W, Brack A, Pham M, Sommer C, Schlegel N, Rittner HL (2024). Dorsal root ganglia atrophy and serum biomarkers supporting the diagnosis of chronic postsurgical inguinal pain. medRxiv, 2024.2006.2018.24309141. https://doi.org/10.1101/2024.06.18.24309141
Piedmont S, Goldhahn L, Swart E, Robra BP, Fleischmann-Struzek C, Somasundaram R, Bauer W. Sepsis im Rettungsdienst : Eine Kohortenstudie zu Screening, Inzidenz und Mortalität [Sepsis in emergency medical services : A cohort study on screening, incidence, and mortality]. Med Klin Intensivmed Notfmed. 2024 Oct;119(7):594-597. German. doi: 10.1007/s00063-024-01183-3. Epub 2024 Sep 26. PMID: 39327270.
Piedmont S, Goldhahn L, Swart E, Robra BP, Fleischmann-Struzek C, Somasundaram R, Bauer W. Sepsis incidence, suspicion, prediction and mortality in emergency medical services: a cohort study related to the current international sepsis guideline. Infection. 2024 Aug;52(4):1325-1335. doi: 10.1007/s15010-024-02181-5. Epub 2024 Feb 19. PMID: 38372959; PMCID: PMC11288994
Schnizer M, Schellong P, Rose N, Fleischmann-Struzek C, Hagel S, Abbas M, Payne B, Evans RN, Pletz MW, Weis S. Long versus short course anti-microbial therapy of uncomplicated Staphylococcus aureus bacteraemia: a systematic review. Clin Microbiol Infect. 2024 Oct;30(10):1254-1260. doi: 10.1016/j.cmi.2024.05.015. Epub 2024 May 30. PMID: 38823452.
Teichmüller K, Rose N, Dreiling J, Schwarzkopf D, Meißner W, Rittner HL, Kindl G. Incidence and treatment of complex regional pain syndrome after surgery: analysis of claims data from Germany. Pain Rep. 2024 Nov 20;9(6):e1210. doi: 10.1097/PR9.0000000000001210. PMID: 39574487; PMCID: PMC11581752.
2023
Bahrs C, Rieg S, Hennigs A, Hitzenbichler F, Brehm TT, Rose N, Jacobi RJ, Heine V, Hornuss D, Huppertz G, Hagel S, Hanses F; German Clinical Study Group in Infectious Diseases (DESTINi). Short-course versus long-course antibiotic treatment for uncomplicated vancomycin-resistant enterococcal bacteraemia: a retrospective multicentre cohort study. Clin Microbiol Infect. 2023 Feb;29(2):200-207. doi: 10.1016/j.cmi.2022.08.023. Epub 2022 Sep 7. PMID: 36087919.
Born S, Fleischmann-Struzek C, Abels W, Piedmont S, Neugebauer E, Reinhart K, Toubekis E, Wegwarth O, Schwarzkopf D. Most patients with an increased risk for sepsis-related morbidity or death do not recognize sepsis as a medical emergency: results of a survey study using case vignettes. Crit Care. 2023 Nov 17;27(1):446.
Born S, Matthäus-Krämer C, Bichmann A, Boltz H, Esch M, Heydt L, Sell S, Streich K, Scherag A, Reinhart K, Hartog CS, Fleischmann-Struzek C. Sepsis Survivors and Caregivers Perspectives on Post–Acute Rehabilitation and Aftercare in the First Year After Sepsis in Germany. Front Med (Lausanne). 2023 Apr 11;10:1137027.
Born S, Matthäus-Krämer C, Reinhart K, Hartog CS, Fleischmann-Struzek C. Satisfaction Among Sepsis Survivors With the Information Received on Their Disease, Its Prevention, and Treatment. Dtsch Arztebl Int. 2023 Dec 15;120(50):871-872.
Fleischmann-Struzek C, Ditscheid B, Rose N, Spoden M, Wedekind L, Schlattmann P, Günster C, Reinhart K, Hartog CS, Freytag A. Return to work after sepsis – A German population-based health claims study. Front Med (Lausanne). 2023 May 25;10:1187809.
Fleischmann-Struzek C, Rudd K. Challenges of assessing the burden of sepsis. Med Klin Intensivmed Notfmed. 2023 Dec;118(Suppl 2):68-74.
Matthäus-Krämer C, Rose N, Spoden M, Pletz MW, Reinhart K, Fleischmann-Struzek C. Urban-rural disparities in case fatality of community-acquired sepsis in Germany: a retrospective cohort study. Int J Environ Res Public Health. 2023 May 18;20(10):5867.
Mellhammar L, Wollter E, Dahlberg J, Donovan B, Olséen CJ, Wiking PO, Rose N, Schwarzkopf D, Friedrich M, Fleischmann-Struzek C, Reinhart K, Linder A. Estimating Sepsis Incidence Using Administrative Data and Clinical Medical Record Review. JAMA Network Open, 6(8), 2023, e2331168-e2331168.
Rose N, Spoden M, Freytag A, Pletz M, Eckmanns T, Wedekind L, Storch J, Schlattmann P, Hartog CS, Reinhart K, Günster C, Fleischmann-Struzek C. Association between hospital onset of infection and outcomes in sepsis patients – a propensity score matched cohort study based on health claims data in Germany. International Journal of Medical Microbiology, 2023, 151593.
Schwarzkopf D, Rose N, Fleischmann-Struzek C, Boden B, Dorow H, Edel A, Friedrich M, Gonnert FA, Götz J, Gründling M, Heim M, Holbeck K, Jaschinski U, Koch C, Künzer C, Le Ngoc K, Lindau S, Mehlmann NB, Meschede J, Meybohm P, Ouart D, Putensen C, Sander M, Schewe JC, Schlattmann P, Schmidt G, Schneider G, Spies C, Steinsberger F, Zacharowski K, Zinn S, Reinhart K. Understanding the biases to sepsis surveillance and quality assurance caused by inaccurate coding in administrative health data. Infection. 2023 Sep 9. doi: 10.1007/s15010-023-02091-y.
Streich K, Hartog CS, Fleischmann-Struzek C, Rose N, Bichmann A, Esch M, Kesselmeier M, Schiefelhövel W, Schmieding M, Born S. Psychometric Properties of the Reintegration to Normal Living Index for sepsis survivors. Qual Life Res. 2023 Mar 30.
Wedekind L, Fleischmann-Struzek C, Rose N, Spoden M, Günster C, Schlattmann P, Scherag A, Reinhart K, Schwarzkopf D. Development and validation of risk-adjusted quality indicators for long-term outcome of acute sepsis care in German hospitals based on administrative claims data. Front Med (Lausanne). 2023 Jan 9;9:1069042.
Winkler D, Rose N, Freytag A, Sauter W, Spoden M, Schettler A, Wedekind L, Storch J, Ditscheid B, Schlattmann P, Reinhart K, Günster C, Hartog CS, Fleischmann-Struzek C. The Effects of Postacute Rehabilitation on Mortality, Chronic Care Dependency, Health Care Use, and Costs in Sepsis Survivors. Ann Am Thorac Soc. 2023 Feb;20(2):279-288. doi: 10.1513/AnnalsATS.202203-195OC. PMID: 36251451.
2022
Debbeler LJ, Pohrt A, Fleischmann-Struek C, Schwarzkopf D, Born S, Reinhart K, Wegwarth O. Effect of Text-Based vs. Graphical Information Formats on Informed Choice in Sepsis Prevention and Early Detection: A Randomized Controlled Trial. J Clin Med. 2022 Jun 24;11(13):3659.
Fleischmann-Struzek C, Ditscheid B, Storch J, Rose N, Spoden M, Hartog CS, Freytag A. Evaluation of Infection-Related Hospitalizations and Drug Prescriptions Among Sepsis Survivors in Germany. JAMA Network Open. 2022;5(7):e2220945.
Fleischmann-Struzek C, Rose N, Born S, Freytag A, Ditscheid B, Storch J, Schettler A, Schlattmann P, Wedekind L, Pletz MW, Sänger S, Brunsmann F, Oehmichen F, Apfelbacher C, Drewitz P, Piedmont S, Denke C, Vollmar HC, Schmidt K, Landgraf I, Bodechtel U, Trumann A, Hecker R, Reinhart K, Hartog CS: White Paper - Verbesserung der Versorgungs- und Behandlungsangebote für Menschen mit Sepsis- und Infektionsfolgen. Dtsch Med Wochenschr 2022; 147(08): 485-491.
Fleischmann-Struzek C, Rose N, Reinhart K. Sepsis-assoziierte Todesfälle in Deutschland: Charakteristika und regionale Variation. [Sepsis-associated deaths in Germany: characteristics and regional variation]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022;65(3):388-395.
Peschke M, Hagel S, Rose N, Pletz MW, Steiner A. Seasonal Influenza Vaccination at a German University Hospital: Distinguishing Barriers Between Occupational Groups. Front Med (Lausanne). 2022 May 27;9:873231. doi: 10.3389/fmed.2022.873231. PMID: 35692542; PMCID: PMC9184714.
Pletz, MW, Dürrwald R, Reiche J, Rose N, Scherag A, Weis S, CoNAN study group. Impact of the COVID-19 pandemic on influenza and RSV antibody titres in the community–a prospective Cohort Study in Neustadt Thuringia/Germany. European Respiratory Journal 2022 60(5): 2200947. doi: 10.1183/13993003.00947-2022
Schwarzkopf D, Rüddel H, Brinkmann A, Fleischmann-Struzek C, Friedrich ME, Glas M, Gogoll C, Gründling M, Meybohm P, Pletz MW, Schreiber T, Thomas-Rüddel DO, Reinhart K. The German Quality Network Sepsis: Evaluation of a Quality Collaborative on Decreasing Sepsis-Related Mortality in a Controlled Interrupted Time Series Analysis. Front Med (Lausanne). 2022 Apr 27;9:882340. doi: 10.3389/fmed.2022.882340. PMID: 35573007; PMCID: PMC9094049.
Spoden M, Hartog CS, Schlattmann P, Freytag A, Ostermann M, Wedekind L, Storch J, Reinhart K, Günster C, Fleischmann-Struzek C. Occurrence and Risk Factors for New Dependency on Chronic Care, Respiratory Support, Dialysis and Mortality in the First Year After Sepsis. Front Med (Lausanne). 2022 May 19;9:878337.
Stallmach A, Kesselmeier M, Bauer M, Gramlich J, Finke K, Fischer A, Fleischmann-Struzek C, Heutelbeck A, Mutschke S, Pletz M, Quickert S, Reinhart K, Stallmach Z, Walter M, Scherag A, Reuken P. Comparison of fatigue, cognitive dysfunction and psychological disorders in post-COVID patients and patients after sepsis: is there a specific constellation? Infection. 2022 Jan 7;1-9.
2021
Born S, Dame C, Matthäus-Krämer C, Reichert F, Schettler A, Schwarzkopf D, Thomas-Rüddel D, Proquitté H, Reinhart K, Fleischmann-Struzek C. Epidemiology of sepsis among children and neonates in Germany – analysis of nationwide DRG data between 2010 and 2016. Crit Care Med. 2021 Feb 23.
Cassini A, Fleischmann-Struzek C, Naghavi M, Reinhart K, Allegranzi B and the WHO Sepsis Expert Technical Group: Future directions and priorities in sepsis epidemiology research: a Call for Action. Bull World Health Organ 2021;99:398–401
Fleischmann-Struzek C*, Kesselmeier M*, Ouart D*, Hartog CS, König C, Braune A, Einhorn C, Chkirni H, Born S, Töpfer K, Romeike H, Reinhart K and Scherag A, for the Mid-German Sepsis Cohort investigators. Cohort profile: The Mid-German Sepsis Cohort (MSC) – an observational patient cohort on long-term sequelae of sepsis survivors. BMJ Open. 2021 Mar 17;11(3):e043352.
Fleischmann-Struzek C, Kesselmeier M, Ouart D, Hartog CS, Bauer M, Bercker S, Bucher M, Meier-Hellmann A, Petros S, Schreiber T, Simon P, Weidhase L, Born S, Braune A, Chkirni H, Eichhorn C, Fiedler S, Gampe C, König C, Platzer S, Romeike H, Töpfer K, Reinhart K, Scherag A. Mid-German Sepsis Cohort (MSC): a prospective observational study of sepsis survivorship. BMJ Open. 2021 Mar 17;11(3):e043352. doi: 10.1136/bmjopen-2020-043352. PMID: 33737430; PMCID: PMC7978081.
Fleischmann-Struzek C, Reichert F, Cassini A, Horner R, Harder T, Kissoon N, Reinhart K, Allegranzi B, Eckmanns T. Global assessment of neonatal sepsis incidence and case fatality. Arch Dis Child 2021;0:1–8.
Fleischmann-Struzek C, Rose N, Freytag A, Spoden M, Prescott HC, Schettler A, Wedekind L, Ditscheid B, Storch J, Born S, Schlattmann P, Günster C, Reinhart K, Hartog CS. Epidemiology and Costs of Postsepsis Morbidity, Nursing Care Dependency, and Mortality in Germany, 2013 to 2017. JAMA Netw Open. 2021 Nov 1;4(11):e2134290. doi: 10.1001/jamanetworkopen.2021.34290. PMID: 34767025; PMCID: PMC8590172.
Fleischmann-Struzek C, Schwarzkopf D, Reinhart K. Inzidenz der Sepsis in Deutschland und weltweit - Eine Übersicht. Med Klin Intensivmed Notfmed. 2021 Jan 28:1-5.
Herrmann L, Kimmig A, Rödel J, Hagel S, Rose N, Pletz MW, Bahrs C. Early Treatment Outcomes for Bloodstream Infections Caused by Potential AmpC Beta-Lactamase-Producing Enterobacterales with Focus on Piperacillin/Tazobactam: A Retrospective Cohort Study. Antibiotics (Basel). 2021 Jun 2;10(6):665. doi: 10.3390/antibiotics10060665. PMID: 34199546; PMCID: PMC8229083.
Karakike E, Giamarellos-Bourboulis EJ, Kyprianou M, Fleischmann-Struzek C, Pletz MW, Netea M, Reinhart K, Kyriazopoulou E. COVID-19 as cause of viral sepsis: A Systematic Review and Meta-Analysis. Crit Care Med. 2021 Jul 12.
Pletz MW, Trommer S, Kolanos S, Rose N, Kinne V, Spott R, Baier M, Lange I. Group Vaccination Five Days before a COVID-19 Outbreak in a Long-Term Care Facility. Vaccines (Basel). 2021 Dec 8;9(12):1450. doi: 10.3390/vaccines9121450. PMID: 34960196; PMCID: PMC8707282.
Rose N, Matthäus-Krämer C, Schwarzkopf D, Scherag A, Born S, Reinhart K, Fleischmann-Struzek C. Association between sepsis incidence and regional socioeconomic characteristics and health care capacity in Germany – An ecological study. BMC Public Health. 2021 Sep 7;21(1):1636.
Rose N, Storch J, Mikolajetz A, Lehmann T, Reinhart K, Pletz M, Forstner C, Vollmar HC, Freytag A, Fleischmann-Struzek C. Preventive effects of influenza and pneumococcal vaccination in the elderly - Results from a population-based retrospective cohort study. Hum Vaccin Immunother. 2021 Jan 7;1-9.
Simpson, A, Long D, Fleischmann-Struzek C, Minogue J, Venkatesh B, Hammond NE, Tian DH, Schlapbach LJ. Long-term functional outcomes for adult and paediatric patients following sepsis – Protocol for a Systematic Review. Front Pediatr. 2021 Oct 25;9:734205.
Storch J, Fleischmann-Struzek C, Rose N, Lehmann T, Mikolajetz A, Maddela S, Pletz MW, Forstner C, Wichmann O, Neufeind J, Vogel M, Reinhart K, Vollmar HC, Freytag A and the vaccination 60+ study group. The effect of influenza and pneumococcal vaccination in the elderly on health service utilization and costs: a claims data-based cohort study. European Journal of Health Economics Eur J Health Econ. 2021 Jul 20.
2020
Fleischmann-Struzek C, Mellhammar L, Rose N, Cassini A, Rudd KE, Schlattmann P, Allegranzi B, Reinhart K. Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis. Intensive Care Med. 2020 Aug;46(8):1552-1562. doi: 10.1007/s00134-020-06151-x. Epub 2020 Jun 22. PMID: 32572531; PMCID: PMC7381468.
Hartog CS, Bodechtel U, Fleischmann-Struzek C, Denke C, Weiss B, Reinhart K. Sepsis: Die Folgen für betroffene Patienten und das Gesundheitssystem [Sepsis: Sequelae for Affected Patients and The Health Care System]. Dtsch Med Wochenschr. 2020 Feb;145(4):252-259. German. doi: 10.1055/a-1019-6379. Epub 2020 Feb 18. PMID: 32069493.
Markwart R, Saito H, Harder T, Tomczyk S, Cassini A, Fleischmann-Struzek C, Reichert F, Eckmanns T, Allegranzi B. Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis. Intensive Care Med 46, 1536–1551 (2020). https://doi.org/10.1007/s00134-020-06106-2
Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, Colombara DV, Ikuta KS, Kissoon N, Finfer S, Fleischmann-Struzek C, Machado FR, Reinhart K, Rowan K, Seymour CW, Watson RS, West TE, Marinho F, Hay SI, Lozano R, Lopez AD, Angus DC, Murray CJL, Naghavi M. Global, regional, and national sepsis incidence and mortality, 1990–2017. Lancet 2020; 395: 200–11
Schmidt K, Gensichen J, Bahr V, Fleischmann-Struzek C, Pausch Ch, Sakr Y, Reinhart K, Vollmar HC, Thiel P, Scherag A, Gantner J, Brunkhorst FM. Long-term survival following sepsis—results of a single-center registry study with four year follow-up. Arztebl Int 2020; 117: 775-82
Schwarzkopf D, Fleischmann-Struzek C, Schlattmann P, Dorow H, Ouart D, Edel A, Gonnert FA, Götz J, Gründling M, Heim M, Jaschinski U, Meybohm P, Putensen C, Sander M, Reinhart K. Investigation of the validity of German inpatient administrative health data for epidemiological surveillance and measurement of quality of care for sepsis – the OPTIMISE study protocol. BMJ Open 2020;10:e035763
2019
Fleischmann-Struzek C, Mikolajetz A, Reinhart K, Curtis RJ, Haase U, Thomas-Rüddel D, Dennler U, Hartog CS. Hospitalization and Intensive Therapy at the End of Life. Dtsch Arztebl Int. 2019 Sep 27;116(39):653-660. doi: 10.3238/arztebl.2019.0653. PMID: 31617481; PMCID: PMC6832106.
Fleischmann-Struzek C, Mikolajetz A, Reinhart K, Curtis JR, Haase U, Hartog CS. Hospitalizations and ICU use in Germany from 2007 to 2015. Dtsch Arztebl Int 2019; 116: 653-60
2018
Betsch C, Rossmann C, Pletz MW, Vollmar HC, Freytag A, Wichmann O, Hanke R, Heinemeier D, Schmid P, Eitze S, Weber W, Reinhardt A, Küpke NK, Neufeind J, Rieck T, Forstner C, Fleischmann-Struzek C, Mikolajetz A, Römhild J, Hanke W, Suchecka K, Reinhart K. Increasing influenza and pneumococcal vaccine uptake in the elderly: Study protocol for the multi-methods prospective intervention study Vaccination60+. BMC Public Health. 2018 Jul 16;18(1):885.
Eitze S, Fleischmann-Struzek C, Betsch C, Reinhart K. Determinants of sepsis knowledge: A representative survey of the elderly population in Germany. Crit Care. 2018 Oct 28;22(1):273.
Fleischmann-Struzek C, Goldfarb DM, Schlattmann P, Schlapbach LJ, Reinhart K, Kissoon N. The global burden of pediatric and neonatal sepsis. Lancet Respir Med. 2018 Mar;6(3):223-230.
Fleischmann-Struzek C, Mikolajetz A, Schwarzkopf D, Cohen J, Hartog CS, Pletz MW, Gastmeier P, Reinhart K. Challenges in Assessing the Burden of Sepsis and Understanding the Inequalities of Sepsis Outcomes between National Health Systems - Secular Trends in Sepsis and Infection Incidence and Mortality in Germany. Intensive Care Med (2018) 44:1826–1835
Fleischmann-Struzek C, Thomas-Rueddel TO, Schettler A, Schwarzkopf D, Stacke A, Seymour CW, Haas C, Dennler U, Reinhart K. Comparing the validity of different ICD coding abstraction strategies for sepsis case identification in German claims data. PLoS One. 2018 Jul 30;13(7):e0198847.
Schwarzkopf D, Fleischmann-Struzek C, Rüddel H, Reinhart K, Thomas-Rüddel DO. A risk model for hospital mortality among patients with severe sepsis or septic shock based on German national administrative claims data. PLoS One. 2018 Mar 20;13(3):e0194371
2017
Fleischmann-Struzek C, Rose N, Freytag A, Spoden M, Prescott HC, Schettler A, Wedekind L, Ditscheid B, Storch J, Born S, Schlattmann P, Günster C, Reinhart K, Hartog CS. Epidemiology and costs of postsepsis morbidity, nursing care dependency, and mortality in Germany, 2013 to 2017. JAMA Netw Open 2021 Nov 1;4(11):e2134290.