Receptor Pharmacology
The group is investigating the localization, regulation and function of G protein-coupled receptors including opioid and somatostatin receptors. We are focusing on the mechanisms of agonist-induced phosphorylation and its physiological relevance for the regulation of signal transduction and tolerance.
Contact:
Tel.: +49 3641 93 25651
Fax: +49 3641 93 25652
Receptor Pharmacology
Colleagues
| apl. Prof. Dr. med. Amelie Lupp, scientist | 93 25 678 |
| Dr. rer. nat. Rainer K. Reinscheid, scientist | 93 25 656 |
| Nina Kathleen Blum; Ph.D. student | 93 25 671 |
| Sebastian Fritzwanker; Dr. rer.nat. | 93 25 667, 93 25 674 |
| Stephanie Kruck; technician | 93 25 661, 93 25 674 |
| Ulrike Schiemenz, Ulrike; technician | 93 25 683, 93 25 693 |
| Stefan Bechmann, technician | 93 25 705, 93 25 653 |
Funded Projects
- DFG: Genetic dissociation of G protein- and arrestin-coupled signaling at the µ-opioid receptor in vivo.
- DFG: Regulated endocytosis and postendocytotic transport of somatostatin receptors.
- DFG: Regulation of opioid tolerance via agonist-selective phosphorylation of endogenous opioid receptors in vivo.
- Deutsche Krebshilfe: Somatostatin receptors as pharmacological targets for diagnostics and therapy.
- SFB: TP C05: Real-time analysis of phosphorylation and dephosphorylation of the μ-opioid receptor.