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RTG 2155 - ProMoAge Halle – Jena

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Principal Investigators

Prof. Dr. Andreas Simm - Spokesperson

Clinic for Heart and Thoracic Surgery,
MLU Halle-Wittenberg and University Hospital Halle

Ernst-Grube Str. 40
06120 Halle (Saale)

phone: +49 345 5572647

SP8 - Histone glycation, cellular senescence and vascular aging - from molecular mechanism to translation

Prof. Dr. Regine Heller - Deputy Spokesperson

Institute of Molecular Cell Biology - CMB,
Jena University Hospital

Hans-Knöll-Str. 2
07745 Jena

phone: +49 3641 9395633

SP13 - Functional characterization of CML modifications in endothelial cells

Prof. Dr. Rüdiger Horstkorte - Steering Committee Member

Institute for Physiological Chemistry,
MLU Halle-Wittenberg

Hollystr. 1
06114 Halle (Saale)

phone: +49 345 5573873

SP2 - The impact of glycosylation and glycation on the generation and uptake of vehicles in aging cells

Prof. Dr. Lars-Oliver Klotz - Steering Committee Member

Institute of Nutritional Sciences, Nutrigenomics Section,
FSU Jena

Dornburger Straße 29
07743 Jena

phone: +49 3641 949751

SP9 - Age-dependent impact of nitrosative stress-induced changes of mineralocorticoid receptor signaling

Prof. Dr. Stefan H. Heinemann - Steering Committee Member

Department of Biophysics - CMB,
FSU Jena and Jena University Hospital

Hans-Knöll-Str. 2
07745 Jena

phone: +49 3641 9395650

SP12 - Visualization of protein modifications and their impact on the electrical signalling

Prof. Dr. Marcus Glomb

Institute for Chemistry - Food Chemistry,
MLU Halle-Wittenberg

Kurt-Mothes-Str. 2
06120 Halle (Saale)

phone: +49 345 5525784

SP1 - Glutathion modulates glycation

Prof. Dr. Heidi Olzscha

Medical School Hamburg,
University of Applied Sciences and Medical University

Am Kaiserkai 1
20457 Hamburg

phone: +49 361 22643303

SP2 - Acetylation and glycosylation in protein folding and misfolding: Impact on ageing-related diseases

Dr. rer.nat. Astrid Gesper

Institute for Physiological Chemistry,
MLU Halle-Wittenberg

Hollystr. 1
06114 Halle (Saale)

phone: +49 345 5573847

SP2 - The impact of glycosylation and glycation on the generation and uptake of vehicles in aging cells

Dr. rer. nat. Kaya Bork

Institute for Physiological Chemistry,
MLU Halle-Wittenberg

Hollystr.1
06114 Halle (Saale)

phone: +49 345 5573824

SP2 - The impact of glycosylation and glycation on the generation and uptake of vehicles in aging cells

Prof. Dr. Anne Navarrete Santos

Dept. of Anatomy and Cell Biology,
MLU Halle-Wittenberg and University Hospital Halle

Große Steinstrasse 52
06108 Halle (Saale)

phone: +49 345 5571718

SP7 - PTM as molecular mechanism for metabolic memory and ageing of adult stem cells

Prof. Dr. Christian Hübner

Institute of Human Genetics,
Jena University Hospital

Am Klinikum 1
07747 Jena

phone: +49 3641 9396800

SP10 - Glycosylation in the aging brain

Prof. Dr. Claudia Großmann

Julius Bernstein Institute of Physiology,
MLU Halle-Wittenberg

Magdeburger Str. 6
06112 Halle (Saale)

phone: +49 345 5574740

SP11 - Age-dependent impact of nitrosative stress-induced changes of mineralocorticoid receptor signaling

Prof. Dr. Otmar Huber

Institute of Biochemistry II,
Jena University Hospital

Nonnenplan 2-4
07743 Jena

phone: +49 3641 9396400

SP14 - The role of Nit1 in aging-associated stress response

Dr. Alessandro Ori

Leibniz Institute on Aging,
Fritz Lipman Institute

Beutenbergstr. 11
07745 Jena

phone: +49 3641 656808

SP15 - Comprehensive Landscape of Age-induced alterations in protein Ubiquitination and Deubiquitination

Prof. Dr. habil. Thorsten Pfirrmann

Health & Medical University Potsdam

Olympischer Weg 1
14471 Potsdam

phone: +49 331 745113202

SP15 - Comprehensive Landscape of Age-induced alterations in protein Ubiquitination and Deubiquitination

Dr. Matthias Jung

Institute for Physiological Chemistry (IPC),
MLU Halle-Wittenberg

Hollystraße 1
06114 Halle (Saale)

phone: +49 345 557 3839

SP16 - Proteostasis at the old blood-brain barrier: Implications for late-onset Alzheimer’s disease

Prof. Dr. Thomas Hollemann

Institute for Physiological Chemistry (IPC),
MLU Halle-Wittenberg

Hollystrasse 1
06114 Halle (Saale)

phone: +49 345 5573812

SP16 - Proteostasis at the old blood-brain barrier: Implications for late-onset Alzheimer’s disease

Dr. habil. Christoph Kaether

Leibniz Institute on Aging,
Fritz Lipmann Institute

Beutenbergstr. 11
07745 Jena

phone: +49 3641 656230

SP17 - Role of PTMs in senescent-induced transformation of the secretory pathway

Dr. Julia von Maltzahn

Leibniz Institute on Aging,
Fritz Lipmann Institute

Beutenbergstr. 11
07745 Jena

phone: +49 3641 656230

SP18 - Molecular differences underlying functional impairment of aged muscle stem cells

Prof. Dr. Steve Hoffmann

Leibniz Institute on Aging,
Fritz Lipmann Institute

Beutenbergstr. 11
07745 Jena

phone: +49 3641 656810

SP19 - Bioinformatics analysis of transcriptional and epigenomic responses to posttranslational modifications

Dr. Alena van Bömmel

Leibniz Institute on Aging,
Fritz Lipmann Institute

Beutenbergstr. 11
07745 Jena

phone: +49 3641 656810

SP19 - Bioinformatics analysis of transcriptional and epigenomic responses to posttranslational modifications

Jun.-Prof. Dr. Florian Meier-Rosar

Research Group Functional Proteomics,
Jena University Hospital

Am Klinikum 1
07747 Jena

phone: +49 3641 9390879

SP20 - Identification of novel O-GlcNAcylated substrates in endothelial cells and investigation of their role in senescence and ageing

Dr. rer. nat. Daria Zibrova

Institute of Molecular Cell Biology - CMB,
Jena University Hospital

Hans-Knöll-Str. 2
07745 Jena

phone: +49 3642 9395635

SP20 - Identification of novel O-GlcNAcylated substrates in endothelial cells and investigation of their role in senescence and ageing

Dr. rer. nat. Patricia Franzka

Institute of Human Genetics,
Jena University Hospital

Am Klinikum 1
07747 Jena

phone: +49 3641 396882

SP21 - The role of GMPPA in the developing and aging brain

Dr. rer. nat. Sonnhild Mittag

Institute of Biochemistry II,
Jena University Hospital

Nonnenplan 2-4
07743 Jena

phone: +49 3641 9396414

SP21 - The role of GMPPA in the developing and aging brain

Prof. Dr. Andrea Henze

Institute of Agricultural and Nutritional Science,
MLU Halle-Wittenberg

Von-Danckelmann-Platz 2
06120 Halle (Saale)

phone: +49 345 5522702

SP22 - Cross-talk of protein oxidation and protein phosphorylation in insulin secretion